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Glutathione depletion is accompanied by increased neuronal nitric oxide synthase activity

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The incubation of endothelial brain cells with gp120 and Tat reduced the GSH intracellular levels and decreased GSH/GSSG ratio

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M1-like macrophages predominantly utilize anabolic metabolism, specifically glycolysis and the PPP, to generate energy and synthesize cellular components, whereas M2-like macrophages are more reliant on OXPHOS, particularly through the enhancement of FAO

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